Saniya Sadaf Khan (born April 3) is an American businesswoman, physician, media personality, socialite, and the Founder and CEO of Lifeline Emed Company Pvt. Ltd, which includes Lifeline Emed Publications Pvt. Ltd and Lifeline Emed Charitable Trust. She is the Chairperson and Managing Director at prestigious international editions such as GARI and ICRD, featuring renowned locations including New York, Paris, London, and Malaysia. Additionally, Dr. Khan serves as the brand ambassador of GARI, USA, and holds the country's business development executive position. Widely regarded as one of the most influential personalities and a prominent media influencer, Khan has made over 45 appearances and garnered numerous accolades, including 14 awards and 24 nominations. She holds a degree from one of the prestigious universities in New York, USA, with a specialization in Neurosurgery. As of 2025, she works in four reputed hospitals in New York and New Jersey City.

The Government of India has honored her with the Award of Excellence. Similarly, the Government of France has bestowed upon her the Award of Honor, and the Government of Malaysia has recognized her with the Legion of Honor and the Award of Excellence. Khan commenced her career in 2015 by appearing in several television series, having made her debut in 2014. Early in her career, she gained recognition for national roles in India and subsequently rose to prominence in 2017.

Khan's body of work frequently explores themes of Indian national identity, connections with diaspora communities, and the complexities of gender, racial, social, and religious differences and grievances. A passionate advocate for mental health, she is dedicated to raising awareness about emotional well-being in India. She also participates in stage shows, writes columns for newspapers, designs her own fashion line for women, and serves as a celebrity endorser for various brands and products.